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KMID : 0043320080310091094
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Archives of Pharmacal Research
2008 Volume.31 No. 9 p.1094 ~ p.1097
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Chemical Constituents from the Flower of Datura metel L.
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Kuang Hai-Xue
Feng Wei-Sheng
Xia Yong-Gang
Yang Bing-You
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Abstract
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Phytochemical investigation of the 50% ethanol eluate fraction of macroporous resin for the flower of Datura metel L. led to the isolation of a new compound named yangjinhualine A (1) and five known megastigmane sesquiterpenes through repeated silica gel and ODS column chromatography and semipreparative HPLC. The structures of these compounds were determined by spectroscopic methods, including 2D-NMR, ESI-MS, and HR-ESI-MS spectrometry as well as by comparison with published data. Five known megastigmane sesquiterpenes were also isolated from D. metel L. for the first time.
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KEYWORD
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Datura metel L., Psoriasis, Solanaceae, Chemical constituents
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